产品货号：
Z37272
中文名称：
ERK2/MAPK1抗体
英文名称：
Anti-ERK2/MAPK1 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-ERK2/MAPK1 Antibody |
| 指标别名 | ERK;ERK 2;ERK2;ERT1;MAP kinase 1;MAP kinase 2;MAP kinase isoform p42;MAPK 1;MAPK 2;MAPK1;MAPK2;p40;p41;p41mapk;p42 MAPK;P42MAPK;PRKM1;PRKM2 |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,ICC/IF |
| 基因名称 | MAPK1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthesized peptide derived from human ERK2 Act as an integration point for multiple biochemical signals,and are involved in a wide variety of cellular processes such as proliferation,differentiation,transcription regulation and development.The activation of ERK2 requires its phosphorylation by upstream kinases.ERK2 is located in the cytoplasm of resting cells and translocates into the nucleus upon extracellular stimuli by active transport of a dimer.ERK2 is essential for placental development and ERK2 in the trophoblast compartment may be indispensable for the vascularization of the labyrinth. |
| 实际分子量 | 41KD |
| 成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
| 纯化方式 | Affinity-chromatography |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Mitogen-activated protein kinase 1,also known as MAPK1,p42MAPK,and ERK2,is an enzyme which in humans is encoded by the MAPK1 gene.The gene is mapped to 22q11.2.And The protein encoded by this gene is a member of the MAP kinase family.The deduced 360-amino acid human ERK2 protein shares 98% identity with rat Erk2.The MAP kinase ERK2 is widely involved in eukaryotic signal transduction.Upon activation,it translocates to the nucleus of the stimulated cell,where it phosphorylates nuclear targets.Futhermore,the ERK pathway is necessary for experience-dependent plasticity and for long-term potentiation of synaptic transmission in the developing visual cortex.And the MAPK pathway is also involved in responses to NTN1. |
| Uniprot ID | P28482 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:20～100ICC/IF Immunocytochemistry/Immunofluorescence(ICC/IF) 1:20～100 |
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